Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity.

نویسندگان

  • E K Stephens
  • Y Tauran
  • A W Coleman
  • M Fitzgerald
چکیده

Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For Gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for Gram- bacteria only calix[6]arenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.

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عنوان ژورنال:
  • Chemical communications

دوره 51 5  شماره 

صفحات  -

تاریخ انتشار 2015